The presence of methamphetamine or amphetamine in a biological sample can have significant import to the individual from whom the sample was taken. The potential for misinterpretation of these results takes on dramatic importance in those circumstances where the results have a significant impact on the individual. Knowledge of the potential origins of amphetamine and methamphetamine in biological samples holds an important place in the area of forensic toxicology. In a clinical emergency setting, it can be important to prevent misinterpretation of the situation and may therefore alter treatment. In workplace drug testing, it can mean the difference between punitive action and no action being taken and in the postmortem arena it can be important in evaluation of the cause of death. This information is also important to programs that focus on driving under the influence, because the presence of these drugs may indicate abuse or legitimate medical use.

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